Optimal HPLC Columns
The Optimal® range of HPLC columns represents the next step forward in porous silica engineering, beyond the so-called "new generation" high purity materials.
The current new generation materials are based on an alternative synthesis route which yields a high purity product with excellent inertness characteristics. However, Optimal is manufactured using an entirely new process based on well established, tried and tested silica production techniques, coupled with new refining technologies ultimately leading to a superior material, combining the advantages of both the new and traditional approaches to silica manufacturing.
Two C18 (ODS) packings are available:
Optimal ODS-H is the most generally applicable of the Optimal phases and can be used for both specialist applications involving acid and basic compounds or mixtures of both.
Optimal ODS-H is also particularly well suited to general purpose method development.
Optimal ODS-L has a slightly lower carbon loading (15%) than the ODS-H and is useful for the analysis of a wide range of hydrophilic compounds which are normally not retained by other C18 based packing material.
One particular advantage is that even pure water can be used as the eluent without the need for any organic modifier. Highly polar samples only soluble in water may be separated by this packing material, e.g. sugars and other saccharides. Optimal ODS-L is also as useful for analyzing hydrophobic samples which are currently chromatographed on competitor C8 materials. Like ODS-H, this packing material is also fully end-capped.
Optimal ODS-L is also based on the same high purity silica as the Optimal ODS-H material which ensures the high degree of inertness and lack of peak tailing.
However, we also supply a complete range of packing materials to cover all standard HPLC applications:
Packings: 120A, 5um